a. Intravenous routes may be obtained by subclavian catheters, implanted ports, or peripherally inserted catheters.
b. Extravasation, the leaking of chemotherapeutic agents into the surrounding tissue, is the major complication of intravenous chemotherapy. Extreme care must be used when administering vesicant agents (chemicals causing damage to tissue on contact)
c. Warning: Never test vein patency with chemotherapeutic agents
d. If extravasion occurs, depending on the chemotherapeutic agents, interventions may include the injection of an antidote, the application of a cold compress, or the application of a warm compress.
e. Monitor the client closely for anaphylactic reactions or serious side effects. Discontinue infusion according to protocol if reactions occur.
f. Use caution when preparing, adminstering, or disposi8ng chemotherapeutic agents. Follow the guuidelines and protective standards for safe handling of chemotherapeutic agentss provided by the Occupational Safety and Health Administration (OSHA) and Oncology Nursing Society.